[There's a long silence, Sasuke not quite sure how to respond -- there's no doubt he'd still be in the village if Itachi had made a different decision all those years ago, but then -- who knows if he'd have even been on this team, were that the case?]

What's done is done, brother. [He pauses again, and then, tone shifting into something that sounds more aggravated:] Anyway, it would have been impossible not to find Naruto annoying, no matter what our circumstances were.